Sunday, August 4, 2013

HTC One, Galaxy S4 GPE Android 4.3 update by OEMs

HTC One, Galaxy S4 GPE Android 4.3 update by OEMs pic 1

Google released Android 4.3 Jelly Bean to Nexus devices about a week ago and finally HTC and Samsung have caught up, today Google has released the new Android 4.3 update for the HTC One GPE and Samsung Galaxy S4 GPE (Google Play Edition).

Many Samsung users are still waiting on a new update to offer either 4.2.2 or 4.3 on their Galaxy S3 or Note 2, but guess the wait will have to carry on. It was a total shock that older devices such as the Galaxy S2 Plus getting its Android 4.2.2 update and the S3 and Note 2 still misses out. The AT&T Samsung Galaxy S3 only got 4.1.2, we just have this feeling the S3 and Note 2 will get Android 4.3 and skip 4.2.2 altogether, but we could be wrong.

Both the Galaxy S3 and Note 2 are great devices, and even though fairly old they still stand up against other phones with great features to boot. Samsung should really consider looking after the customers they have rather than keep releasing smartphones if they know they cant keep up with software updates, its madness.

HTC One, Galaxy S4 GPE Android 4.3 update by OEMs

Anyway, back to the news at hand. Google has released the new Android 4.3 update for the HTC One and Samsung Galaxy S4 GPE, it seems they will release updates for Google Play Edition devices quicker than any other. Why is GPE devices getting preferential treatment and the likes of the S3 and Note 2 miss out? We will let you answer this one.

Android Police says the new 4.3 update for Google Play Edition HTC One and S4 in about 150MB in size and developed by OEMs, which means no carrier testing or modifications to the UI will get in the way.

There are a few changes with this update, offering custom changes such as support for Bluetooth tethering, larger icons on widget panels, grey background in settings menus which means the Samsung black background has been replaced, users will get to see small changes to the camera and interface.

Thanks to this update with Bluetooth Tethering surely users will be able to use the Samsung Galaxy Google Play Edition with Google Glass. You can get the Android 4.3 update right now OTA by going into Settings ? About phone ? System updates menu on your device.

Have you received the Android 4.3 update on your HTC One or Samsung Galaxy GPE handset yet?

Source: http://www.phonesreview.co.uk/2013/08/03/htc-one-galaxy-s4-gpe-android-4-3-update-by-oems/

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Ohio killer set for execution found hanged in cell

CLEVELAND (AP) ? A man condemned to death for fatally stabbing a neighbor during a Cleveland burglary was found hanged in his cell Sunday just days before his Wednesday execution.

Billy Slagle, 44, was found at about 5 a.m. at the Chillicothe Correctional Institution south of Columbus and was declared dead within the hour, prison spokeswoman JoEllen Smith said.

"He was in his cell alone. No other inmates suspected to be involved," Smith said in an email. "It does appear to be a suicide."

Under regular prison policy, he was scheduled to be placed under pre-execution watch Sunday morning but "was not yet placed under constant watch," Smith said.

Slagle was sentenced to die for the 1987 stabbing of Mari Anne Pope, who was killed while two young children she was watching were in the house.

In a rare move, the prosecutor in Cleveland asked the Ohio Parole Board to spare Slagle. Cuyahoga County Prosecutor Tim McGinty said jurors today, with the option of life without parole, would be unlikely to sentence Slagle to death.

The parole board and Gov. John Kasich both rejected mercy for Slagle.

Last week, Slagle's attorney argued that a jury never got the chance to hear the full details of his troubled childhood.

The attorneys, arguing for a new trial and to delay his execution, said that information met requirements for asking for a new trial, which normally must happen within four months of a conviction.

Slagle was "unavoidably prevented" from filing his request because his original attorneys didn't develop and present the evidence, the filing said.

McGinty and Slagle's attorneys had cited his age ? at 18, he was barely old enough for execution in Ohio ? and his history of alcohol and drug addiction.

___

Associated Press writer Julie Carr Smyth in Columbus contributed to this report

Source: http://news.yahoo.com/ohio-killer-set-execution-found-hanged-cell-144043776.html

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Amid Grading Controversy, Florida Education Chief Tony Bennett Resigns

Tony Bennett resigned Thursday as Florida education commissioner following two days of controversy over school grades in his home state of Indiana.

He made the announcement at a news conference in Tallahassee late Thursday morning.

?The decision to resign is mine and mine alone, because I believe that when this discussion turns to an adult, we lose the discussion about making life better for children,? Bennett said.

Coming to Florida from the Hoosier state last January, Bennett had faced mounting calls for his resignation in the wake of revelations, first reported by The Associated Press, that he interceded on behalf of an Indiana charter school run by a prominent Republican Party donor. On Thursday, he called those reports ?malicious and unfounded.?

His resignation would be a major setback for Gov. Rick Scott and state education leaders, who are working to overhaul Florida?s system of school accountability and assessment in compliance with the national Common Core standards.

?I?m saddened by Commissioner Bennett?s departure,? state Board of Education member Sally Bradshaw wrote in an email to the Herald/Times. ?This is a loss for Florida?s students.?

The Florida Department of Education has had a revolving door of leaders during Scott?s 31 months in office. Including Bennett, there have been three different education commissions and two interim education commissioners.

Bennett, a nationally recognized education reformer, came on board after losing reelection in Indiana.

Source: http://www.governing.com/news/state/Amid-Grading-Controversy-Florida-Education-Chief-Tony-Bennett-Resigns.html

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Saturday, August 3, 2013

Dover 10-year-olds fall in state baseball

The Dover 10-year-old baseball team finished third in the state after falling to Galion 10-9 in eight innings in the losers? bracket final at Hamilton on Friday night.

Both of Dover?s losses in the tournament came in extra innings.

Reese Klar had four singles and Brennan McCune smacked a home run and two singles. Ayden Hall added a double and single and Nathan Ravine had a double for Dover.

Galion plays West Side Hamilton tonight for the state title.

On Thursday, Dover outlasted Canfield 14-12 to reach the losers? bracket final.

Ravine had four singles to lead Dover. McCune smacked a home run and triple.

Reese Klar added three singles and Hall, Evan Klar and Will McCrate had two singles each. Carter Stamets had a double.

Hall was the winning pitcher and Ravine recorded the save.
?

?

Source: http://www.timesreporter.com/newsnow/x369944547/Dover-10-year-olds-fall-in-state-baseball?rssfeed=true

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Cobalt replacements make solar cells more sustainable

Cobalt replacements make solar cells more sustainable [ Back to EurekAlert! ] Public release date: 2-Aug-2013
[ | E-mail | Share Share ]

Contact: Reto Caluori
reto.caluori@unibas.ch
41-612-672-495
University of Basel

Researchers at the University of Basel have successfully replaced the rare element iodine in copper-based dye-sensitized solar cells by the more abundant element cobalt, taking a step forward in the development of environmentally friendly energy production. The journal Chemical Communications has published the results of these so-called Cu-Co cells.

Dye-sensitized solar cells (DSCs) transform light to electricity. They consist of a semiconductor on which a dye is anchored. This colored complex absorbs light and through an electron transfer process produces electrical current. Electrolytes act as electron transport agents inside the DSCs.

Usually, iodine and iodide serve as an electrolyte. Chemists at the University of Basel have now been able to successfully replace the usual iodine-based electron transport system in copper-based DSCs by a cobalt compound. Tests showed no loss in performance.

The replacement of iodine significantly increases the sustainability of solar cells: Iodine is a rare element, only present at a level of 450 parts per billion in the Earth, whereas cobalt is 50 times more abundant, explains the Project Officer Dr. Biljana Bozic-Weber. Furthermore, this replacement also removes one of the long-term degradation processes in which copper compounds react with the electrolyte to form copper iodide and thus improves the long-term stability of DSCs.

The research group around the Basel chemistry professors Ed Constable and Catherine Housecroft is currently working on optimizing the performance of DSCs based on copper complexes. They had previously shown in 2012 that the very rare element ruthenium in solar cells could be replaced by copper derivatives.

This is the first report of DSCs, which combine copper-based dyes and cobalt electrolytes and thus represents a critical step towards the development of stable iodide-free copper solar cells. However, many aspects relating to the efficiency need to be addressed before commercialization can begin in anything other than niche markets.

Molecular Systems Engineering

In changing any one component of these solar cells, it is necessary to optimize all other parts as a consequence, says Ed Constable. This is part of a new approach termed Molecular Systems Engineering in which all molecular and material components of a system can be integrated and optimized to approach new levels of sophistication in nanoscale machinery. In this publication, the engineering of the electrolyte, the dye and the semiconductor are all described.

This systems chemistry approach is particularly appropriate for the engineering of inorganic-biological hybrids and is the basis of ongoing collaborations with the ETH Department of Biosystems Engineering in Basel (D-BSSE) and EMPA. A joint proposal by the University of Basel and D-BSSE for a new National Centre of Competence in Research in this area is currently in the final stages of appraisal.

###

Original Citation

Biljana Bozic-Weber, Edwin C. Constable, Sebastian O. Frer, Catherine E. Housecroft, Lukas J. Troxler and Jennifer A. Zampese
Copper(I) dye-sensitized solar cells with [Co(bpy)3]2 /3 electrolyte
Chem. Commun., 2013,49, 7222-7224 | doi: 10.1039/C3CC44595J


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Cobalt replacements make solar cells more sustainable [ Back to EurekAlert! ] Public release date: 2-Aug-2013
[ | E-mail | Share Share ]

Contact: Reto Caluori
reto.caluori@unibas.ch
41-612-672-495
University of Basel

Researchers at the University of Basel have successfully replaced the rare element iodine in copper-based dye-sensitized solar cells by the more abundant element cobalt, taking a step forward in the development of environmentally friendly energy production. The journal Chemical Communications has published the results of these so-called Cu-Co cells.

Dye-sensitized solar cells (DSCs) transform light to electricity. They consist of a semiconductor on which a dye is anchored. This colored complex absorbs light and through an electron transfer process produces electrical current. Electrolytes act as electron transport agents inside the DSCs.

Usually, iodine and iodide serve as an electrolyte. Chemists at the University of Basel have now been able to successfully replace the usual iodine-based electron transport system in copper-based DSCs by a cobalt compound. Tests showed no loss in performance.

The replacement of iodine significantly increases the sustainability of solar cells: Iodine is a rare element, only present at a level of 450 parts per billion in the Earth, whereas cobalt is 50 times more abundant, explains the Project Officer Dr. Biljana Bozic-Weber. Furthermore, this replacement also removes one of the long-term degradation processes in which copper compounds react with the electrolyte to form copper iodide and thus improves the long-term stability of DSCs.

The research group around the Basel chemistry professors Ed Constable and Catherine Housecroft is currently working on optimizing the performance of DSCs based on copper complexes. They had previously shown in 2012 that the very rare element ruthenium in solar cells could be replaced by copper derivatives.

This is the first report of DSCs, which combine copper-based dyes and cobalt electrolytes and thus represents a critical step towards the development of stable iodide-free copper solar cells. However, many aspects relating to the efficiency need to be addressed before commercialization can begin in anything other than niche markets.

Molecular Systems Engineering

In changing any one component of these solar cells, it is necessary to optimize all other parts as a consequence, says Ed Constable. This is part of a new approach termed Molecular Systems Engineering in which all molecular and material components of a system can be integrated and optimized to approach new levels of sophistication in nanoscale machinery. In this publication, the engineering of the electrolyte, the dye and the semiconductor are all described.

This systems chemistry approach is particularly appropriate for the engineering of inorganic-biological hybrids and is the basis of ongoing collaborations with the ETH Department of Biosystems Engineering in Basel (D-BSSE) and EMPA. A joint proposal by the University of Basel and D-BSSE for a new National Centre of Competence in Research in this area is currently in the final stages of appraisal.

###

Original Citation

Biljana Bozic-Weber, Edwin C. Constable, Sebastian O. Frer, Catherine E. Housecroft, Lukas J. Troxler and Jennifer A. Zampese
Copper(I) dye-sensitized solar cells with [Co(bpy)3]2 /3 electrolyte
Chem. Commun., 2013,49, 7222-7224 | doi: 10.1039/C3CC44595J


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-08/uob-crm080213.php

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Friday, August 2, 2013

China, India prepare for joint military exercise

from The BRICS Post:

China and India are finalising the schedule for a third joint counter-terrorism exercise between their armies announced during?India?s Defence Minister A K Antony?s visit to China last month.

A delegation of the Chinese Army is scheduled to visit India in the last week of August to hold a planning conference in the eastern Indian city of Kolkata.

The two-week long Hand-in-Hand exercise between China and India will be held in October in the?Chengdu region of China, according to Indian news agency PTI.

The first two exercises were held in 2007 and 2008.

Read More @ TheBRICSPost.com

Source: http://sgtreport.com/2013/08/china-india-prepare-for-joint-military-exercise/

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Will the new iPad mini come with Retina display?

O

f all the iPad mini's drawbacks, the 8-inch tablet's relatively steep price-point ($329) and glaring lack of a high-definition screen were far and away the biggest arguments against buying one. So it isn't entirely unexpected that Apple, according to a new report in the Wall Street Journal, is preparing an HD version, with an eye toward a fall release just before the holidays:

Apple is working with suppliers in Asia on its next iPad mini with a high-resolution "retina" display, unlike the current iPad mini that comes with a lower-resolution screen, the people said. The size of the new tablet will likely be the same as the current 7.9-inch model, which was released in November last year. Apple has also been contemplating multiple color back covers for the new tablet, they said. [Wall Street Journal]

Now, the report does note that Apple "routinely tests various designs and has been known to make changes late in the design process," so a high-definition iPad mini may not actually hit the market. And one of the juicier nuggets from the report is that at least a few of the high-def screens will be supplied by one of Apple's most formidable rivals: Samsung. (The other suppliers are said to be LG and Sharp.)

However, it's worth pointing out that the new version of Google's awesome Nexus 7 tablet was released just last week with an HD screen. Not only is it $100 cheaper than the iPad mini, but it's deservedly racking up rave reviews.

Mind you, bumping the iPad mini up to HD could come with tradeoffs. As TIME's Jared Newman notes, "It takes more power to handle all those pixels." A Retina-equipped mini will need a much better processor (A5X?) crammed into the tablet's smaller body, meaning reduced battery life. Or you could give its chassis an icky size-bump to squeeze in a larger power source.

And while an HD screen sounds like the most obvious upgrade the iPad mini could receive at this point, 9to5 Mac points to an iOS 7 SDK file that seems to allude to an iPad mini with a faster A6 processor, but no Retina. Obviously, that would be a much harder feature to sell to consumers, especially in light of the Nexus 7's turbo-charged upgrades.

Source: http://theweek.com/article/index/247745/will-the-new-ipad-mini-come-with-retina-display

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OS X Mavericks preview: Sprite Kit simplifies 2D game development

OS X Mavericks preview: Sprite Kit simplifies 2D game development

New technology coming to OS X Mavericks promises to make it easier for indie gamers to support the platform with 2D arcade-style games. What's more, it's portable between Mavericks and iOS 7. Sprite Kit promises to reinvent the way 2D games are made for the Mac.

Sure, 3D games are cool, but there's been a strong push over the past few years to produce killer games with "old school" appeal - games that reference the 2D platformers, puzzlers and action games of old. After all, many gamers these days grew up in the shadow of Nintendo consoles - heck, some of us old farts even had Ataris, back in the day - and feel really comfortable playing those types of games.

Apple is answering the call by rolling its own frameworks for 2D game development, which it calls Sprite Kit. "Sprites" in 2D game development parlance are the animated characters you see in a computer game - the character you control, the bad guys, the bullets and missiles, and all the other elements of a scene in a game that's overlaid on top of the background.

But Sprite Kit controls a lot more than just characters in games. It's a complete engine for managing things like in-game physics. It also provides a particle system that helps developers produce more realistic effects like fire, smoke and explosions. That can save developers a lot of time from having to learn how to do these things using low-level technology like OpenGL, the graphics open standard that OS X supports.

Here's what Apple says on its public web page for Mavericks developers:

Create high-performing 2D games with the powerful new Sprite Kit framework, which allows you to control sprite attributes such as position, size, rotation, gravity, and mass. Sprite Kit?s OpenGL-based renderer efficiently animates 2D scenes.

Why Sprite Kit is a good idea

There are plenty of "middleware" offerings from software development companies who make money by licensing their technology to game developers who want to develop titles, but don't want to "roll their own" low level technology to handle things line in-game physics and animation. Some of those licenses are available at low cost, too, or in some cases, free, depending on how many copies of the game are sold.

But that technology is, by and large, not custom-designed specifically for OS X and iOS. Sprite Kit's different is that it's home-grown by Apple, so developers can expect better integration with Apple's Xcode development environment and better support at the core operating system level.

That's a net win for developers who begin to use the new technology, since maintaining compatibility with new operating system releases and changes to core Apple technology can be a real pain.

Sprite Kit won't have all the same features as more mature and robust game development engines will, at least not right off the bat. But it'll be enough for game developers to produce some compelling titles right away, and just like other core OS technology and development frameworks, Apple's certain to improve it over time.

Bridging the gap between iOS and OS X

In so many ways, Apple is trying to sensibly erase the line between using an iOS device and using a Mac - we see this in Mavericks technologies like iCloud Keychain, which just work regardless of which device you're using.

Sprite Kit exists very much in that realm - it's a technology that will be supported both by iOS 7 and Mavericks, to make it easier for developers to move in between those worlds, creating games that can run on any Apple-branded device, instead of limiting themselves to a single market.

Are you a Mavericks developer? Are you going to use Sprite Kit to create your games? Or do you prefer to use a third-party game engine technology? Let me know.

    


Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/LD6G0wpRjGM/story01.htm

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Rihanna-Chris Brown Breakup: All About Trust!

Source: http://www.thehollywoodgossip.com/2013/07/rihanna-chris-brown-breakup-all-about-trust/

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Thursday, August 1, 2013

Arnold Schwarzenegger to launch line of nutritional supplements ...

Arnold Schwarzenegger arrives for the European Premiere of The Last Stand at a central London cinema in Leicester Square, Tuesday, Jan. 22, 2013. (Photo by Joel Ryan/Invision/AP)

Former California governor and bodybuilder Arnold Schwarzenegger is launching a new line of nutritional supplements in September. His Arnold Series supplements will focus on four areas: performance, power and strength, nutrient support and recovery.

"I?ve been on a crusade to promote fitness for more than four decades," Schwarzenegger said. "That has led to the largest health and fitness convention in the world, six books, seminars all over the globe and visits to all 50 states as chairman of the President?s Council on Physical Fitness."

He?s partnering with Denver-based MusclePharmCorp. Schwarzenegger said that after meeting with the MusclePharm team, learning about the company, and spending time with the founders, he knew they would be the perfect partners.

The series will be available domestically and internationally at health and nutrition stores as well as online retailers in September.


Copyright 2013 The Salt Lake Tribune. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.sltrib.com/sltrib/money/56665889-79/schwarzenegger-arnold-supplements-fitness.html.csp

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Twitter reportedly hiring for its new office in Sunnyvale

SUNNYVALE -- Metaphorically speaking, the size of the workforce about to occupy Twitter's first-ever Silicon Valley outpost in Sunnyvale is quite a few characters shy of a full tweet.

The 8,000-square-foot office, which was first reported in May, can accommodate 40 or 50 employees, a drop in the bucket for a company that employed more than 900 as of 2012. Now some of those staffers may soon be on the premises.

"I can confirm that we have begun to hire for our Sunnyvale office,'' Twitter spokeswoman Christina Thiry said Tuesday, declining to offer any more details. The San Francisco micro-blogging site agreed in May to lease the space at Sunnyvale Business

(FILES) The Twitter logo is displayed at the entrance of Twitter headquarters in San Francisco in this March 11, 2011 file photo. KIMIHIRO HOSHINO/AFP/Getty Images (KIMIHIRO HOSHINO)

Park at 400 W. California Ave. near the Caltrain station in downtown Sunnyvale, according to brokers with Colliers International and Jones Lang LaSalle, the commercial realty firms that arranged the lease.

"This is a big deal for this area, a tech company from San Francisco opening an office in Silicon Valley," Kevin Moul, a broker with Colliers, told this newspaper at the time. "It's good to see some movement from San Francisco to Silicon Valley."

Sunnyvale's economic development manager Connie Verceles did not immediately return a phone call Tuesday for comment..

Twitter's albeit humble foray into the South Bay not only helps boost tech hiring in an already red-hot area of job growth, but it's also one more factor to weigh in the emerging debate between San Francisco and San Jose over what Silicon Valley really means anymore.

As of Tuesday afternoon, a single job posting appeared under listings for the Sunnyvale office on Twitter's website. It said Twitter was in the market for a "Software Engineer, Core Runtime Diagnostics," adding that the perfect candidate should be "obsessed with root causing complex systems issues and helping others do the same.''

Included in the list of job requirements, the ad

said applicants must be "proficient with one or more: gdb, perf, oprofile, wireshark" and other developer tools for Linux, a computer operating system.

But that's not all. Along with seeking someone with Linux experience, Twitter said it wanted this from its prospective employees:

"You are awesome, passionate, and nice."

Staff writer George Avalos contributed to this story. Contact Patrick May at 408-920-5689; follow him at Twitter.com/patmaymerc.

Source: http://www.siliconvalley.com/ci_23760987/twitter-reportedly-hiring-its-new-office-sunnyvale?source=rss_viewed

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U.S. U-18 Men?s National Team opens Milk Cup with 1-1 draw vs. Mexico

Sorry, Readability was unable to parse this page for content.

Source: http://www.facebook.com/PotomacSoccerWire/posts/10151752356504634

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Wednesday, July 31, 2013

US government will declassify Yahoo documents and court decision by September

DNP US government will declassify Yahoo FISA documents by September

Earlier this month, the US government was put in the hot seat with regards to the Justice Department's 2008 battle with Yahoo over its request for user data. Yahoo fought the PRISM demand and ultimately lost; five years later, we're finally going to be able to see the court decision that's been kept under lock and key since then. The clock is ticking for the federal government, as the Foreign Intelligence Surveillance Court has set a September deadline for unveiling those classified documents. While this might be a victory for transparency, it's important to remember that declassification doesn't necessarily mean full disclosure. The government will still have the option to redact certain portions of text that it feels must remain classified. Considering its reticence to share the information in the first place, we can probably expect to see a liberal distribution of those pesky black rectangles.

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Via: GigaOM

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/2Pa58no4dNY/

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Migraine, Cluster, or Tension Headaches: The Different Types of ...

So, your head hurts. What do you do?

When it comes to headache treatment, it all depends on what type of headache you have to begin with. Although some headache types are vastly different?migraine is the only type of headache accompanied by the sensory symptoms known as aura, for example?others share common symptoms and triggers and are frequently misdiagnosed.

At least at home. Often, a patient comes in claiming sinus headache, without any of the congestion, fever or other symptoms of a true infection, says Robert Cowan, M.D., professor of neurology and director of the headache program at Stanford University. Most likely, it's actually a migraine, he says, and "all the antibiotics in the world aren't going to help it."

The most common type of headache is tension-type, says Cowan, which can be brought on by stress, anxiety, alcohol, or eye strain as well as other triggers. Cluster headaches and medication overuse headaches (formerly known as rebound headaches) are also relatively common. Sinus headaches are much rarer, he says, but not as rare as more troubling syndromes Cowan has treated, including SUNCT headaches, in which patients experience brief stabbing pains as many as hundreds of times a day that require IV medication to treat.

Of course, your head might hurt because of direct trauma, such as a car accident or sports injury, says Dawn C. Buse, Ph.D., associate professor of neurology at the Albert Einstein College of Medicine of Yeshiva University and the director of behavioral medicine at Montefiore Headache Center. Others experience what are known as exertion headaches, she says, which can occur after coughing, exercise, or even sex.

RELATED: 9 Ways to Prevent Allergies?Without Meds!

While a headache specialist may be your best bet at an accurate diagnosis, knowing the answers to a few key questions can help you and your doctor arrive at the right treatment plan.

"It's really helpful to have your headache history organized," says Cowan. Knowing how long your headaches last, how severe they are, how frequent they are, and what triggers them can paint a picture for your doctor when you're not currently experiencing pain. "You have to pay attention to your life," he says, just like a person with asthma has to pay attention to the weather when exercising outside.

Below are some of the crucial questions you should keep track of when it comes to your headaches?and a basic picture of what the answers might mean.

Sources: Johns Hopkins Medical Center, National Institutes of Health, WebMD, ProMyHealth, Stanford Medicine, Montefiore Headache Center

More on Huffington Post Healthy Living:
Is Hot Yoga Dangerous?
Why You Should Say No to Diet Soda
Fitness Experts' Fave Moves

Source: http://www.shape.com/lifestyle/mind-and-body/what-your-headache-trying-tell-you

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Tuesday, July 30, 2013

A Low Roller Guide to Poker in London - (PTP News Feed)

A Low Roller Guide to Poker in London

This series will bring you paired guides to the world?s true poker capitals, a high roller and low roller guide, providing the full spread of low-downs on how to ball it poker-style, be it high or lowball. We?ll start the series with a low roller guide to London.

LONDON LOW ROLLER GUIDE

London, freaking expensive European capital of stinking wealth. You really have to watch your wallet here if you?re not rolling in cash ?cause this city will eat your money without pausing for breath. It?s a beautiful, rich, dirty capital of capital and it?s up to you to survive in it and enjoy it. Even the locals complain about the prices, in a city where cheap drinks will cost you twice what they do an hour?s ride out of town. It gets away with it all by being a hell of a lot of fun.

The games

A great selection of games exist for the small to midstakes player. Cash games a-plenty can be found from ?1 ? ?1 at?The Vic?, the Victoria Grosvenor Casino. The Empire in Leicester Square, reputedly host to the softest cash games in the capital, also runs cash games through the night starting at ?1 ? ?2 with a ?50 minimum.

Many casinos and poker rooms exist across London, and sites such as The London Poker Guide can be of help in sifting through your options, or indeed in picking a tournament to take part in last minute.

I say last minute, while in fact you must be careful in London to pre-register with ID at many poker venues some time before attending, often 24 hours before. Just phone up before fixing your plans, to find out whether a particular casino or poker room requires this.

If you fancy trying to satellite into a live event running in the capital, London is host to its own leg of the EPT, to the GUKPT, the WPT and the UKIPT (United Kingdom and Ireland Poker Tour) Grand Final each year.

To eat

There are some amazing options in London that won?t kill your roll. I?ll give you the lowdown on a few of them here.

If you?re after cuisine with a kick, and want something authentic, try Mestizo for a great Mexican experience. Just a little north of the centre, three minutes walk from the nearest underground station and it?s the real deal.

Dishoom will provide you with some premium Indian cuisine in the heart of central London, Covent Garden. As spicy as its Mexican counterpart but from the other side of the world, both these cuisines are immensely popular across the UK.

Forget those chain fast food outlets, Patty and Bun in Bond Street is where it?s at for burgers in London. You?ll mind the queues less once you bite into one.

If you?re on a serious budget, you can move it a big notch down and focus on the food for a fiver approach. Some pubs offer very decent offers on certain days of the week, and Chinatown, right next to Leicester Square, is beautifully cheap and full of buffets (some of which are all you can eat!).

Talking of budget food, be sure to try out some of the numerous all day breakfasts available in London on literally every corner. Some are divine, some hideous. It all depends on the quality of meat used, and other ingredients.

In case you?re unfamiliar, the standard fare in a full English breakfast includes sausages, bacon, mushrooms, beans, toast, tomatoes and frequently chips, black pudding (basically dried blood ? avoid if not hugely carnivorous!) and hash browns. You won?t need lunch after one of these!

Going out

If clubbing?s your thing, you?re going to like London. One club which gets a lot of press in London is Fabric, a large venue running three rooms of beats throughout the night. Trips to Fabric tend to be marathon affairs so be prepared for an all-nighter.

The Ministry of Sound, a legendary institution, also runs its own club in London. You can get a taste of this club without even attending, as they run a ?live from the club? radio on the website.

Shamelessly stealing its name from an enlightened being, funkybuddha is a very hip venue doing well in central London and worth a look.

If you?d rather navigate your own way through the capital, TimeOut London, probably the most popular information hub on the capital, can provide excellent guidance.

To stay

For some serious value for money, check out some of these options.

With a very central location, great ratings and rooms from ?50 a night, the Ridgemount hotel is a fine option. Her Majesty Hotel prides itself on providing top notch accommodation, in particular to business travellers, and is priced in the same range.

For something a little extravagant without the price tag, lastminute.com offers an interesting service. They will provide you with a room in a five star hotel, but the hotel itself and location (within London) will remain a mystery until the day of your check in. Known as the ?secret hotel? service, this proves a real winner with those who don?t mind too much about which part of the city they bed down in, and you pay amazingly low rates for five star accommodation.

To relax

I?m not talking about sight-seeing. Sight-seeing is not relaxing, whether it?s crammed into a tour bus or rushing around the bridges of central London with a million other malcontents. I?m talking about peace, however contradictory that might sound in London.

?**** Take a walk in one of the massive parks of the capital, totally free of charge. I recommend Hyde Park, Regent?s Park and Green Park as fine options.

?**** If you want to go further into nature in the city, take a visit to Kew Royal Botanical Gardens. Host to thousands of species of plant, this is really a very special place. It?s not free, but it?s well worth the entry fee of ?14.50.

?**** Go relax in one of London?s many spas.

This series is written by Luke Haward. Luke is a writer, editor, MTT grinder and poker coach based in Oxford, UK and Guadalajara, Mexico. His interests include game design, charity, ecology and philosophy. You can follow him on Twitter @LukeHaward.

Source: http://forum.parttimepoker.com/shooting-off-sponsored-carbon-poker/949723-low-roller-guide-poker-london-ptp-news-feed.html

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Facebook refuses UN request on Somali pirates

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NAIROBI, Kenya ? United Nations investigators hoped they would get some help from Facebook when they asked to see information on suspected pirates operating in Somalia.

But Facebook refused.

A report by the U.N. Monitoring Group on Somalia and Eritrea this month pointed out that while many private companies helped in the group's investigative work on matters such as piracy, al-Qaida-linked militants and government corruption, Facebook provided no such assistance.

"Despite repeated official correspondence addressed to Facebook Inc., it has never responded to Monitoring Group requests to discuss information on Facebook accounts belonging to individuals involved in hijackings and hostage-taking," the report said.

Facebook said in a statement Tuesday that the U.N. group had no legal authority to demand data from the company. "We therefore declined their request and referred them to law enforcement authorities," the company said in an e-mailed statement.

Facebook's refusal to share information with U.N. investigators comes as reverberations continue from the disclosure by Edward Snowden, a former contractor for the National Security Agency, that the NSA has cooperated with companies as Yahoo, Google and Facebook to access emails, video chats and pictures. U.S. officials have said the program is narrowly focused on foreign targets, and technology companies say they turn over information only if required by court order.

"Facebook has faced such pressures relating to privacy and the use of account information in various jurisdictions, even just for marketing purposes, that I would expect them to be very cautious about sharing personal information even with a U.N. Monitoring Group," said Matt Bryden, a former coordinator of the Somalia monitoring group.

Pirates use social networks
The nearly 500-page U.N. report said that investigations have confirmed that numerous piracy facilitators "are interlinked through various communication channels and employ social network services, such as Facebook."

In any case, two Somali pirates who spoke to The Associated Press said pirates don't use social networks for piracy work.

"There are more personal accounts than general ones for the pirates," said Bile Hussein, a Somali pirate commander in Gracad, a pirate base in central Somalia by phone. "We use emails for deals."

"Many of us keep our distance away from the Internet to avoid getting tracked or captured," said another pirate, Hassan Abdi.

The U.N. Monitoring Group would have been interested in access to non-public phone numbers and email addresses that might be listed on Facebook accounts, or to see what "friends" a pirate might have, said Bryden, now the director of Sahan Research, a think tank focusing on peace and security in the Horn of Africa

A page in Facebook's "Safety Center" titled "Information for Law Enforcement Authorities" says that a valid subpoena in connection with a criminal investigation is required to compel the disclosure of basic subscriber records. If a matter could result in the imminent harm of a child or risk of death or serious injury, a law enforcement official is asked to contact Facebook.

The U.N. Monitoring Group does not have subpoena power. Bryden said international companies often resist, at least at first, assisting the U.N. group because the companies aren't familiar with its work or authority.

"All it has is the force of the Security Council mandate that requests all member states and private entities ... to assist the Monitoring Group's efforts, so cooperation varies considerably," Bryden said.

Bradley Shear, a Washington D.C.-based lawyer who runs a blog focusing on social media law, noted that Facebook frequently cooperates with U.S. law enforcement officials investigating issues surrounding child safety, but he speculated that Facebook may be reluctant to help a U.N. body because the U.N. is trying to become involved with Internet regulation.

Shear said Facebook is not likely to be legally culpable just because Somali pirates or members of al-Shabab use their social media platforms.

"In general, absent knowledge that illegal activity is occurring on your platform, social/digital media platforms have little legal liability for the illegal activity that is occurring on their websites," Shear wrote in an email. "However, there is a growing trend to hold social media/digital media operators accountable for the illegal content/activity on their websites if they turn a blind eye towards it."

Social media use by al-Shabab militants in Somalia is common. Twitter shut down the account of an al-Shabab spokesman earlier this year after the micro-blogging site was used to post a hostage video and death threat, posts that violated Twitter's terms of service.

A new Twitter handle that the U.N. Monitoring group believes is run by a British member of al-Shabab opened a short time later and remains in use.

Associated Press reporter Abdi Guled in Mogadishu, Somalia, and Technology Writer Barbara Ortutay in New York contributed to this report.

? 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

Source: http://feeds.nbcnews.com/c/35002/f/663301/s/2f5ac54f/sc/11/l/0L0Snbcnews0N0Ctechnology0Cfacebook0Erefuses0Eun0Erequest0Esomali0Epirates0E6C10A7980A21/story01.htm

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Be Mine! Why Monogamy Evolved in Mammals

Male primates may have become monogamous to protect their offspring from being killed by rival males, a new study finds. However, others disagree, saying monogamy evolved in mammals so that males could guard their mates.

A team of British and Australian researchers compared data across 230 primate species over 75 million years, and found that the threat of infanticide ? specifically, the threat of baby primates being killed by unrelated males ? likely triggered monogamy.

Since infants are dependent on their mothers throughout childhood, and since female primates typically delay further conception while they are nurturing their young, male competitors may see advantages in doing away with babies that their rivals have sired, said study lead author Christopher Opie, a postdoctoral research fellow in the department of anthropology at the University College London in the United Kingdom. [8 Humanlike Behaviors of Primates]

"For a male who knows he's not the father of an infant, it can pay for him to kill that infant, because then he can make sure the female comes back into ovulation. And he can mate with her," Opie told LiveScience. "It's a way for males to try to increase their genes that are passed into the next generation."

The researchers examined the prevalence of infanticide across different primate species over time and found links between this threat and the onset of monogamy.

"When we looked across all 230 species, we saw that infanticide evolved at different points, but in all cases, it had already evolved by the time monogamy evolved," Opie said. The results were published online today (July 29) in the journal Proceedings of the National Academy of Sciences (PNAS).

Another study out today, however, suggests monogamy may have evolved to protect females against competition from other females.

Neither study purports to explain monogamy in people. "We are cautious about making any definite statement about monogamy in humans," study researcher Tim Clutton-Brock of the University of Cambridge said in a press briefing, adding that when it comes to monogamy, "humans are obviously fantastically variable."

Primate family tree

Only 3 percent to 5 percent of all mammals bond for life, but researchers have long debated the evolution of monogamy, with scientists trying to pinpoint when in history animals displayed monogamous tendencies ? and why.

To trace monogamy's evolutionary pathway, Opie and his colleagues constructed a giant family tree based on genetic data of the relationships among the species of primates. The researchers then used statistical models to identify where behavioral changes ? such as the emergence of paternal care of offspring or the ranging patterns of females ? likely occurred throughout the primates' evolutionary history.

"We effectively simulate evolution millions of times across the family tree and get probabilities for how each of the behaviors would change over time," Opie explained.

This technique resembles the one used by famed American statistician Nate Silver when he predicts the results of presidential elections, and the method used by Google when it produces search engine results, Opie said.

The models determined that male infanticide coincided with the switch from behavior in which females mated with multiple males, to monogamy in primates. The results also suggest that other behaviors, such as paternal care, resulted from monogamy. [The Animal Kingdom's Most Devoted Dads]

"In all the species where males provide care, monogamy already evolved in those species," Opie said. "So, we can see an evolutionary pathway where infanticide evolved first, then as one of the responses to that, monogamy evolved, and then in those species ? but not all ? paternal care evolved."

A far-reaching analysis?

While the study offers insight into the evolution of monogamy, the results are highly dependent on how the researchers classified the various species of primates, said Eduardo Fernandez-Duque, an associate professor of anthropology at the University of Pennsylvania in Philadelphia, who was not involved in the new study.

Fernandez-Duque, who has studied monogamy and paternal care in primates for 20 years, noted some inconsistencies in the descriptions of a few of the species, such as the classification that some primates in the genus Callicebus are sexually monogamous but not socially monogamous (they don't stay together to raise the offspring, for instance).

In addition, "the researchers treat infanticide as binary, which makes me a little uncomfortable," Fernandez-Duque told LiveScience. "For example, they categorize infanticide as high or low, but there's no room for species that don't show infanticide."

Still, Fernandez-Duque says the research represents exciting progress in the field of primatology, and he hopes to look deeper into the data.

Tracing the evolution of monogamy

Another study, this one detailed today in the journal Science, suggests monogamy evolved to allow males to protect females.

Using a new genetic classification technique, the researchers of the new study inferred how species were related and when they split off from one another in the evolutionary tree. The scientists classified each species as solitary (living alone), socially monogamous (living in breeding pairs) or as group-living. A total of 2,500 mammalian species were involved. [The Wild Kingdom: Take Our Animal Sex Quiz]

Then the scientists simulated how solitary females might evolve social monogamy versus how group-living females might evolve the trait. Researchers used sophisticated statistical methods to determine which scenarios were more likely.

Social monogamy evolved 61 times among the animals studied, the analysis showed. All but one of these transitions involved solitary females, rather than group-living females. In addition, the common ancestor of all mammals was solitary.

The findings suggest that for species in which females lived alone in large territories to avoid competition for food and other resources, males were unable to defend multiple females, and therefore became monogamous.

"In mammals, social monogamy is the result of resource distribution," study researcher Dieter Lukas, of the University of Cambridge, said in a press briefing today. Females were limited by the distribution of food, and males were limited by the distribution of females, Lukas said.

Social monogamy was also more common among primates and carnivores than other species, the study found. The more specialized diets of these animals may have increased competition for food, leading females to isolate themselves.

The findings failed to support the idea that the risk of infanticide led to monogamy in mammals, even in primates. The researchers suggest the discrepancy between the two studies could be explained by differences in how group-living is classified. For instance, some species that Opie's team classified as group-living were classified by Lukas as socially monogamous. Alternatively, the smaller sample of animals in Opie's study could have skewed their findings, Lukas and his colleagues said.

However, both studies found that parental care was more likely a consequence, not a cause, of the evolution of monogamy.

Follow?Tanya Lewis on Twitter?and Google+ & Denise Chow on Twitter @denisechow. Follow LiveScience @livescience, Facebook?& Google+. Original article on?LiveScience.com.

Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/mine-why-monogamy-evolved-mammals-231528117.html

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Monday, July 29, 2013

Ouya Game Console Owners Not Playing Games - internet TV

The Ouya Kickstarter-funded android based game console has been eagerly awaited by gamers. And since the launch it seems the eagerness has evaporated, as a mere 27% (or less than a third) have paid for a single game.

ouya-games-consoleThe $99 console launched last month is by definition a cheap entry into the console market, and will appeal to those that are fed up with paying $40-60 for a game,? but it would be like buying a new Xbox one and not bothering to buy a game!

Many android games are of the ?freemium? variety, that is you can download a free version and pay if you want extra level or the full version. And of course, the android system makes for a great streaming device and XBMC media platform.

Most early buyers of the fledgling game console have been crowdsource investors, so possible the console is more of a trophy than a working product, and it could be that the second wave of public Ouya buyers may be a little less ?tight?.

Speaking to The Verge CEO of Ouya, Julie Uhrman put on a brave face saying that sales have been, ?better than expected,? and that, ? For 13 of the top 20 games on the system, at least eight percent of free downloads are converted into a paid purchase.?

And pointing to the fact is has literally just been released she said, ?I think there are a lot of social and mobile app developers that would kill for an 8 percent attach rate on a platform that?s 30 days old. These numbers will grow as more gamers pick up consoles and as we attract more developers, and I believe that by the end of the year we?ll see a few developers telling us they?ve made more than a million dollars on Ouya.?

As if the low sales are not bad enough, soon Ouya will have to contend with a rival android console from Google according to the WSJ. They report that the search engine giant are designing and marketing the device themselves following the success of Android which powers over 75% of all smartphones.

Welcome to WorldTVPC Blog dedicated to bringing the latest news from the world of online tv, streaming services and TV hardware. We have news, links and a comprehensive review section. Hope you enjoy and we welcome all constructive comments

Steve Sanger

Latest TV searches:

games, android console, games WWW, android game console, android games console, free games, ouya gaming console, ouya play old pc games, wii u games available now

Source: http://www.worldtvpc.com/blog/ouya-game-console-owners-not-playing-games/

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NIH expands study to better understand kidney disease progression

NIH expands study to better understand kidney disease progression [ Back to EurekAlert! ] Public release date: 29-Jul-2013
[ | E-mail | Share Share ]

Contact: Bill Polglase
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Researchers from the Chronic Renal Insufficiency Cohort (CRIC) study are embarking on another five years of work to identify risk factors for progression of early stage chronic kidney disease (CKD), better understand the importance of reduced kidney function in older persons, and learn what role CKD may play in other illnesses that require hospitalization. CRIC is supported by the National Institutes of Health.

A major goal of the next five years is to recruit 1,500 people to the existing group of nearly 4,000 study participants. According to Dr. Harold Feldman, the principal investigator of the study's Scientific and Data Coordinating Center at the University of Pennsylvania, Philadelphia, this additional time will allow researchers to collect more data needed to explore and build upon findings compiled over the past 10 years, and examine in much greater detail the broad range of illnesses experienced by people with CKD.

"The original volunteers have aged since the study began. By extending the study, we're able to look more closely at an older population a crucial time since most people who develop kidney failure that requires dialysis or a kidney transplant do so in their early 60s," said Dr. Robert Star, director of the Division of Kidney, Urologic, and Hematologic Diseases at NIH's National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). "Studying older individuals with CKD is an area of considerable interest, so unlike the original cohort where participants were broadly aged -- between 21 and 74 years at study entry -- those invited to join now will be between the ages of 45 and 79."

Dialysis is a treatment to filter wastes and excess fluid from the blood, a task normally performed by the kidneys. Most people with kidney failure are attached to a dialysis machine for three to four hours at a time, three times per week.

Another important feature of the new study participants is that they will have better kidney function or less severe disease -- known as mild to moderate CKD -- than the original study participants. They will also be screened for protein in the urine, a sign of kidney damage. Most of the U.S. population with CKD has mild to moderate disease.

"By more closely studying a group with better kidney function, we can try to learn how to prevent kidney disease," Star said. "We want to better understand the risk factors for worsening of kidney function to design new strategies for treatment of CKD and its complications."

Lastly, although the CRIC study investigators carefully studied the association of cardiovascular disease with CKD, recent analyses revealed that many patients were hospitalized frequently for respiratory and digestive illnesses. This finding led study investigators to plan to collect more information on the impact of CKD on hospitalizations, according to Star. "Together with expanding the existing study population to include additional older patients and earlier stages of CKD, this fresh approach amounts to a regeneration of the CRIC study that will map out a whole new way to evaluate the impact of CKD," he said. "Although the relationship between CKD and cardiovascular disease is still a major focus, since it's the big killer among CKD patients, the CRIC study will examine more closely these other related illnesses that impact so significantly on patients' overall functioning and health."

Feldman added that the study will continue, in accordance with applicable data privacy laws and policies, to send study data and specimens from all participants to the Central NIDDK Repositories. All data and specimens are made available to a wider research community to expand the usefulness of the study.

An estimated 20 million or more American adults have CKD, and over 400,000 people in the United States and 2 million worldwide depend on dialysis to treat kidney failure. CKD costs the nation $44 billion per year, or roughly 18 percent of total Medicare expenditures, and kidney failure carries a cost of $33 billion, according to NIH's U.S. Renal Data System.

The CRIC study is one of the largest and longest ongoing studies of CKD epidemiology in the U.S. It is a collaboration among 13 U.S. clinical sites Case Western Reserve University, Cleveland; the Cleveland Clinic, Cleveland; Johns Hopkins Medical Institutions, Baltimore; Kaiser Permanente Northern California, Oakland, Calif.; MetroHealth Cleveland, Cleveland; St. Johns Medical Center, Detroit; Tulane University, New Orleans; University of California San Francisco, San Francisco, Calif.; University of Illinois, Champagne, Ill.; University of Maryland, College Park, College Park, Md.; University of Michigan, Ann Arbor, Mich.; University of Pennsylvania, Philadelphia; and Wayne State University, Detroit. The study's Scientific and Data Coordinating Center is at the University of Pennsylvania.

New findings have emerged from the CRIC study already, including the discovery that a high level of fibroblast growth factor 23, a hormone that regulates the amount of phosphate in the blood, has been linked to a significantly increased risk of death and kidney failure.

###

The CRIC study (ClinicalTrials.gov number: NCT00304148) is supported under NIH grant U01DK060990. For more information, including published results, visit http://www.cristudy.org.

The NIDDK, a component of the NIH, conducts and supports research on diabetes and other endocrine and metabolic diseases; digestive diseases, nutrition and obesity; and kidney, urologic and hematologic diseases. Spanning the full spectrum of medicine and afflicting people of all ages and ethnic groups, these diseases encompass some of the most common, severe and disabling conditions affecting Americans. For more information about the NIDDK and its programs, see http://www.niddk.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


NIH expands study to better understand kidney disease progression [ Back to EurekAlert! ] Public release date: 29-Jul-2013
[ | E-mail | Share Share ]

Contact: Bill Polglase
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Researchers from the Chronic Renal Insufficiency Cohort (CRIC) study are embarking on another five years of work to identify risk factors for progression of early stage chronic kidney disease (CKD), better understand the importance of reduced kidney function in older persons, and learn what role CKD may play in other illnesses that require hospitalization. CRIC is supported by the National Institutes of Health.

A major goal of the next five years is to recruit 1,500 people to the existing group of nearly 4,000 study participants. According to Dr. Harold Feldman, the principal investigator of the study's Scientific and Data Coordinating Center at the University of Pennsylvania, Philadelphia, this additional time will allow researchers to collect more data needed to explore and build upon findings compiled over the past 10 years, and examine in much greater detail the broad range of illnesses experienced by people with CKD.

"The original volunteers have aged since the study began. By extending the study, we're able to look more closely at an older population a crucial time since most people who develop kidney failure that requires dialysis or a kidney transplant do so in their early 60s," said Dr. Robert Star, director of the Division of Kidney, Urologic, and Hematologic Diseases at NIH's National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). "Studying older individuals with CKD is an area of considerable interest, so unlike the original cohort where participants were broadly aged -- between 21 and 74 years at study entry -- those invited to join now will be between the ages of 45 and 79."

Dialysis is a treatment to filter wastes and excess fluid from the blood, a task normally performed by the kidneys. Most people with kidney failure are attached to a dialysis machine for three to four hours at a time, three times per week.

Another important feature of the new study participants is that they will have better kidney function or less severe disease -- known as mild to moderate CKD -- than the original study participants. They will also be screened for protein in the urine, a sign of kidney damage. Most of the U.S. population with CKD has mild to moderate disease.

"By more closely studying a group with better kidney function, we can try to learn how to prevent kidney disease," Star said. "We want to better understand the risk factors for worsening of kidney function to design new strategies for treatment of CKD and its complications."

Lastly, although the CRIC study investigators carefully studied the association of cardiovascular disease with CKD, recent analyses revealed that many patients were hospitalized frequently for respiratory and digestive illnesses. This finding led study investigators to plan to collect more information on the impact of CKD on hospitalizations, according to Star. "Together with expanding the existing study population to include additional older patients and earlier stages of CKD, this fresh approach amounts to a regeneration of the CRIC study that will map out a whole new way to evaluate the impact of CKD," he said. "Although the relationship between CKD and cardiovascular disease is still a major focus, since it's the big killer among CKD patients, the CRIC study will examine more closely these other related illnesses that impact so significantly on patients' overall functioning and health."

Feldman added that the study will continue, in accordance with applicable data privacy laws and policies, to send study data and specimens from all participants to the Central NIDDK Repositories. All data and specimens are made available to a wider research community to expand the usefulness of the study.

An estimated 20 million or more American adults have CKD, and over 400,000 people in the United States and 2 million worldwide depend on dialysis to treat kidney failure. CKD costs the nation $44 billion per year, or roughly 18 percent of total Medicare expenditures, and kidney failure carries a cost of $33 billion, according to NIH's U.S. Renal Data System.

The CRIC study is one of the largest and longest ongoing studies of CKD epidemiology in the U.S. It is a collaboration among 13 U.S. clinical sites Case Western Reserve University, Cleveland; the Cleveland Clinic, Cleveland; Johns Hopkins Medical Institutions, Baltimore; Kaiser Permanente Northern California, Oakland, Calif.; MetroHealth Cleveland, Cleveland; St. Johns Medical Center, Detroit; Tulane University, New Orleans; University of California San Francisco, San Francisco, Calif.; University of Illinois, Champagne, Ill.; University of Maryland, College Park, College Park, Md.; University of Michigan, Ann Arbor, Mich.; University of Pennsylvania, Philadelphia; and Wayne State University, Detroit. The study's Scientific and Data Coordinating Center is at the University of Pennsylvania.

New findings have emerged from the CRIC study already, including the discovery that a high level of fibroblast growth factor 23, a hormone that regulates the amount of phosphate in the blood, has been linked to a significantly increased risk of death and kidney failure.

###

The CRIC study (ClinicalTrials.gov number: NCT00304148) is supported under NIH grant U01DK060990. For more information, including published results, visit http://www.cristudy.org.

The NIDDK, a component of the NIH, conducts and supports research on diabetes and other endocrine and metabolic diseases; digestive diseases, nutrition and obesity; and kidney, urologic and hematologic diseases. Spanning the full spectrum of medicine and afflicting people of all ages and ethnic groups, these diseases encompass some of the most common, severe and disabling conditions affecting Americans. For more information about the NIDDK and its programs, see http://www.niddk.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-07/niod-nes072913.php

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